🧠 Category
Cognitive & Nootropic Peptides
Neuropeptides researched for memory, focus, neuroprotection, and mood — several developed in Eastern European clinical settings.
Neuropeptides researched for memory, focus, neuroprotection, and mood — several developed in Eastern European clinical settings.
Cognitive and nootropic peptides are studied for memory, focus, mood, and neuroprotection. A striking feature of this category is its geography: many of the best-known compounds — Semax, Selank, Cerebrolysin, Noopept, Cortexin — were developed and are used clinically in Russia and neighboring countries, but have limited independent Western clinical evidence.
Others, like dihexa and the CNTF-derived P21, are potent in animal models of cognition but have never been tested in humans. Davunetide is an instructive exception — it reached large Western trials for a tauopathy and did not work. Across the category, treat dramatic cognitive claims with caution: the gap between Russian clinical practice, preclinical potency, and proven Western efficacy is wide.
A neuropeptide developed in Russia (related to ACTH(4-10)) and used there clinically, studied for cognition, neuroprotection, and stroke recovery.
Read the guide →A synthetic peptide based on the immune fragment tuftsin, developed in Russia as an anxiolytic and studied for anxiety, mood, and cognition.
Read the guide →A peptide preparation derived from pig brain tissue, used in several countries for stroke, traumatic brain injury, and dementia — with a mixed and debated evidence base.
Read the guide →A small peptide derived from angiotensin IV, studied in animal models for promoting new synapse formation and cognitive enhancement, with potency attributed to the HGF/c-Met system.
Read the guide →A naturally occurring neuropeptide named for early reports of sleep-promoting effects, studied for sleep, stress resilience, and pain — but still poorly characterized.
Read the guide →A natural hormone and neuropeptide central to bonding, birth, and lactation — FDA-approved for obstetric use (as Pitocin) and widely researched (often intranasally) for social and emotional behavior.
Read the guide →A small neurotrophic compound derived from a region of ciliary neurotrophic factor (CNTF), studied in animal models for promoting neurogenesis and protecting against neurodegeneration.
Read the guide →A polypeptide preparation extracted from animal cerebral cortex, used in Russia and nearby countries for stroke, brain injury, and cognitive conditions.
Read the guide →A short “peptide bioregulator” (Glu-Asp-Arg) from the Khavinson research line, studied for brain function, neuroprotection, and age-related decline.
Read the guide →A short neuroprotective peptide derived from activity-dependent neuroprotective protein (ADNP), studied for tau-related neurodegeneration and cognition.
Read the guide →A proline-containing dipeptide nootropic developed in Russia, studied for memory, neuroprotection, and mild cognitive complaints — and used there clinically.
Read the guide →They are used clinically in Russia and have supportive Russian studies, but large independent Western trials are lacking, so their cognitive benefits are not well established by international standards. None is FDA-approved.
No. Compounds such as Semax, Selank, Cerebrolysin, Noopept and Cortexin are not FDA-approved. They are used as medicines in some countries but are sold elsewhere as research chemicals or supplements of uncertain legal standing.
Several (like Semax and Selank) are formulated as intranasal solutions because they would be broken down if swallowed, while Noopept is reported to be orally active. We do not publish dosing protocols — these are matters for qualified medical guidance.